Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
synrgSynergin, gamma. (1464 aa)    
Predicted Functional Partners:
ENSACLP00000003396
AP-1 complex subunit gamma.
    
 0.967
LOC113023456
Aftiphilin a.
   
 0.966
aftph
Clathrin_bdg domain-containing protein.
   
 0.966
ENSACLP00000012866
Uncharacterized protein.
   
 0.959
ENSACLP00000012873
SH3 domain-containing protein.
   
 0.959
ENSACLP00000014175
Intersectin 2b.
   
 0.959
LOC113010505
AP-1 complex subunit gamma.
    
 0.928
ENSACLP00000016469
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.926
ENSACLP00000000836
Intersectin 1 (SH3 domain protein).
   
 0.920
ENSACLP00000001080
Uncharacterized protein.
   
 0.920
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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