Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007805Matrix metallopeptidase 17b. (589 aa)    
Predicted Functional Partners:
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.756
LOC113020696
TIMP metallopeptidase inhibitor 2b.
    
 0.742
TIMP2
TIMP metallopeptidase inhibitor 2.
    
 0.742
LOC113034822
Heparin-binding EGF-like growth factor a.
    
 0.719
pla2g4a
Phospholipase A2.
     
  0.676
LOC113023444
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
    
 0.637
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
    
 0.637
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 2.
    
 0.631
ncf4
Neutrophil cytosolic factor 4.
   
 
 0.624
edn1
Endothelin 1.
     
 0.591
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.