fpgs protein (Astatotilapia calliptera) - STRING interaction network

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fpgs

Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (579 aa)

Predicted Functional Partners:

dhfr

0.943

tyms

0.933

LOC113027086

0.921

LOC113033411

0.912

LOC113022169

0.896

LOC113029321

0.896

mthfd1

0.839

ENSACLP00000023470

0.839

ENSACLP00000028179

0.839

ENSACLP00000015215

0.823

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000015215	ENSACLP00000023470	ENSACLP00000015215	ENSACLP00000023470	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	THF_DHG_CYH domain-containing protein.	0.945
ENSACLP00000015215	ENSACLP00000028179	ENSACLP00000015215	ENSACLP00000028179	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.956
ENSACLP00000015215	LOC113027086	ENSACLP00000015215	ENSACLP00000006486	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Zgc:153031.	0.911
ENSACLP00000015215	dhfr	ENSACLP00000015215	ENSACLP00000008879	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Dihydrofolate reductase.	0.933
ENSACLP00000015215	fpgs	ENSACLP00000015215	ENSACLP00000007851	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.823
ENSACLP00000015215	mthfd1	ENSACLP00000015215	ENSACLP00000005354	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.	0.945
ENSACLP00000015215	tyms	ENSACLP00000015215	ENSACLP00000001614	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	Thymidylate synthetase.	0.935
ENSACLP00000023470	ENSACLP00000015215	ENSACLP00000023470	ENSACLP00000015215	THF_DHG_CYH domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.945
ENSACLP00000023470	ENSACLP00000028179	ENSACLP00000023470	ENSACLP00000028179	THF_DHG_CYH domain-containing protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.871
ENSACLP00000023470	LOC113027086	ENSACLP00000023470	ENSACLP00000006486	THF_DHG_CYH domain-containing protein.	Zgc:153031.	0.924
ENSACLP00000023470	dhfr	ENSACLP00000023470	ENSACLP00000008879	THF_DHG_CYH domain-containing protein.	Dihydrofolate reductase.	0.937
ENSACLP00000023470	fpgs	ENSACLP00000023470	ENSACLP00000007851	THF_DHG_CYH domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.839
ENSACLP00000023470	tyms	ENSACLP00000023470	ENSACLP00000001614	THF_DHG_CYH domain-containing protein.	Thymidylate synthetase.	0.941
ENSACLP00000028179	ENSACLP00000015215	ENSACLP00000028179	ENSACLP00000015215	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.956
ENSACLP00000028179	ENSACLP00000023470	ENSACLP00000028179	ENSACLP00000023470	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	THF_DHG_CYH domain-containing protein.	0.871
ENSACLP00000028179	LOC113027086	ENSACLP00000028179	ENSACLP00000006486	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Zgc:153031.	0.946
ENSACLP00000028179	dhfr	ENSACLP00000028179	ENSACLP00000008879	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Dihydrofolate reductase.	0.968
ENSACLP00000028179	fpgs	ENSACLP00000028179	ENSACLP00000007851	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.839
ENSACLP00000028179	mthfd1	ENSACLP00000028179	ENSACLP00000005354	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.	0.871
ENSACLP00000028179	tyms	ENSACLP00000028179	ENSACLP00000001614	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	Thymidylate synthetase.	0.933

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