fpgs protein (Astatotilapia calliptera) - STRING interaction network

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fpgs

Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (579 aa)

Predicted Functional Partners:

tyms

0.910

dhfr

0.906

nudt15

0.901

LOC113027086

0.890

LOC113022169

0.871

LOC113033411

0.869

LOC113034258

0.866

LOC113033300

0.866

bcat1

0.865

LOC113020289

0.865

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113020289	bcat1	ENSACLP00000033768	ENSACLP00000011283	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.832
LOC113020289	fpgs	ENSACLP00000033768	ENSACLP00000007851	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.865
LOC113020289	tyms	ENSACLP00000033768	ENSACLP00000001614	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Thymidylate synthetase.	0.766
LOC113022169	LOC113027086	ENSACLP00000009564	ENSACLP00000006486	Folate gamma-glutamyl hydrolase.	Zgc:153031.	0.860
LOC113022169	LOC113033411	ENSACLP00000009564	ENSACLP00000019786	Folate gamma-glutamyl hydrolase.	Folate gamma-glutamyl hydrolase.	0.835
LOC113022169	dhfr	ENSACLP00000009564	ENSACLP00000008879	Folate gamma-glutamyl hydrolase.	Dihydrofolate reductase.	0.862
LOC113022169	fpgs	ENSACLP00000009564	ENSACLP00000007851	Folate gamma-glutamyl hydrolase.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.871
LOC113022169	tyms	ENSACLP00000009564	ENSACLP00000001614	Folate gamma-glutamyl hydrolase.	Thymidylate synthetase.	0.872
LOC113027086	LOC113022169	ENSACLP00000006486	ENSACLP00000009564	Zgc:153031.	Folate gamma-glutamyl hydrolase.	0.860
LOC113027086	LOC113033300	ENSACLP00000006486	ENSACLP00000035564	Zgc:153031.	Uncharacterized protein.	0.886
LOC113027086	LOC113033411	ENSACLP00000006486	ENSACLP00000019786	Zgc:153031.	Folate gamma-glutamyl hydrolase.	0.877
LOC113027086	LOC113034258	ENSACLP00000006486	ENSACLP00000012803	Zgc:153031.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.886
LOC113027086	dhfr	ENSACLP00000006486	ENSACLP00000008879	Zgc:153031.	Dihydrofolate reductase.	0.856
LOC113027086	fpgs	ENSACLP00000006486	ENSACLP00000007851	Zgc:153031.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.890
LOC113027086	nudt15	ENSACLP00000006486	ENSACLP00000040252	Zgc:153031.	Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family.	0.417
LOC113027086	tyms	ENSACLP00000006486	ENSACLP00000001614	Zgc:153031.	Thymidylate synthetase.	0.993
LOC113033300	LOC113027086	ENSACLP00000035564	ENSACLP00000006486	Uncharacterized protein.	Zgc:153031.	0.886
LOC113033300	LOC113034258	ENSACLP00000035564	ENSACLP00000012803	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.830
LOC113033300	dhfr	ENSACLP00000035564	ENSACLP00000008879	Uncharacterized protein.	Dihydrofolate reductase.	0.886
LOC113033300	fpgs	ENSACLP00000035564	ENSACLP00000007851	Uncharacterized protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.866

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