close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC1130305903-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa)    
Predicted Functional Partners:
cdc25b
Rhodanese domain-containing protein.
    
 0.955
LOC113033717
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.943
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.943
yap1
Yes-associated protein 1.
    
 0.940
bad
BCL2 associated agonist of cell death b.
    
  0.903
LOC113036202
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
  
0.873
LOC113030401
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
  
0.873
ENSACLP00000030835
TSC complex subunit 2.
    
 0.849
nedd4
NEDD4 E3 ubiquitin protein ligase a.
    
 0.823
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
    
 0.823
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.