Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACLP00000007885Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (259 aa)    
Predicted Functional Partners:
ENSACLP00000035345
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
     
 0.947
wsb1
WD repeat and SOCS box containing 1.
    
 
 0.872
wsb2
WD repeat and SOCS box containing 2.
    
 
 0.872
usp33
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.798
usp20
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.798
ENSACLP00000032711
RING-CH-type domain-containing protein.
    
   0.740
ENSACLP00000034356
Membrane-associated ring finger (C3HC4) 6.
    
   0.740
thrb
Thyroid hormone receptor beta.
      
 0.729
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.724
LOC113014940
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
      
 0.718
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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