Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC113035360Phosphoribosyl pyrophosphate synthetase 1B. (318 aa)    
Predicted Functional Partners:
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
  
 
0.983
LOC113021041
Pribosyltran_N domain-containing protein.
  
 
0.983
LOC113021448
Phosphoribosyl pyrophosphate synthetase-associated protein 2.
  
 
0.983
ENSACLP00000022352
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.957
umps
Uridine monophosphate synthetase.
  
 
 0.956
rbks
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.956
rpia
Ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase).
  
 
 0.954
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
  
 0.947
pgm2l1
Phosphoglucomutase 2-like 1.
  
 0.939
pgm2
Phosphoglucomutase 2.
  
 0.939
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (40%) [HD]