Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
calhm6Calcium homeostasis modulator family member 6. (326 aa)    
Predicted Functional Partners:
c22h1orf109
C19h1orf109 homolog (H. sapiens).
   
    0.740
rubcnl
Rubicon like autophagy enhancer.
   
    0.733
cwc25
CWC25 spliceosome associated protein homolog.
   
    0.731
fbxo47
F-box domain-containing protein.
   
    0.721
mocs3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
    0.713
ENSACLP00000004042
Limb and CNS expressed 1.
   
    0.686
LIX1L
Limb and CNS expressed 1 like.
   
    0.686
ACOT11
Acyl-CoA thioesterase 11a.
   
    0.684
acot11
Acyl-CoA thioesterase 11b.
   
    0.684
LOC113010508
Ig-like domain-containing protein.
   
    0.674
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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