Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vps37bVPS37B subunit of ESCRT-I. (282 aa)    
Predicted Functional Partners:
vps28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
    
 0.999
mvb12a
Uncharacterized protein.
   
 0.998
LOC113027041
Zgc:123278.
   
 0.992
tsg101
Tumor susceptibility 101a.
   
 0.992
vps25
Vacuolar protein sorting 25 homolog.
    
 0.991
mvb12b
Multivesicular body subunit 12Ba.
   
 0.989
ENSACLP00000020055
Multivesicular body subunit 12Bb.
   
 0.989
vps36
Vacuolar protein sorting 36 homolog.
    
 0.975
snf8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
    
 0.971
vps37a
VPS37A subunit of ESCRT-I.
     
0.962
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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