Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000007983Poly [ADP-ribose] polymerase. (594 aa)    
Predicted Functional Partners:
LOC113033185
Si:dkey-3h3.3.
   
 
 0.906
dtx3
Zgc:66440.
   
 
 0.833
ifih1
Interferon induced with helicase C domain 1.
   
 
 0.772
ENSACLP00000033620
RING-type domain-containing protein.
  
 
 0.699
ENSACLP00000008219
Macro domain-containing protein.
 
    
0.608
LOC113035099
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
  
 
 0.598
LOC113030349
H2A histone family, member Y; Belongs to the histone H2A family.
  
 
 0.598
LOC113007473
Uncharacterized protein.
  
 
0.592
parp3
Poly [ADP-ribose] polymerase.
    
 
 0.592
ENSACLP00000002986
RING-type domain-containing protein.
   
 
 0.531
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.