STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK2Non-specific serine/threonine protein kinase. (513 aa)    
Predicted Functional Partners:
LOC113022989
Cell division cycle 42.
   
 0.993
pak1
Non-specific serine/threonine protein kinase.
   
  0.982
PAK3
Non-specific serine/threonine protein kinase.
   
  0.982
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
   
 0.977
arhgef7
Rho guanine nucleotide exchange factor (GEF) 7a.
   
 0.977
LOC113015990
Rho guanine nucleotide exchange factor (GEF) 7b.
   
 0.977
nck2
Cytoplasmic protein.
    
 0.972
nck1
Cytoplasmic protein.
    
 0.972
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
  0.937
LOC113015068
Cell division cycle 42, like.
   
 0.934
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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