STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK2Non-specific serine/threonine protein kinase. (513 aa)    
Predicted Functional Partners:
LOC113022989
Cell division cycle 42.
   
 0.973
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.965
arhgef7
Rho guanine nucleotide exchange factor (GEF) 7a.
    
 0.965
LOC113015990
Rho guanine nucleotide exchange factor (GEF) 7b.
    
 0.965
nck2
Cytoplasmic protein.
    
 0.953
nck1
Cytoplasmic protein.
    
 0.953
LOC113031477
Uncharacterized protein.
   
 0.933
RAC1
Rac family small GTPase 1.
    
 0.909
map3k2
Mitogen-activated protein kinase kinase kinase 2.
    
0.905
map3k3
Mitogen-activated protein kinase kinase kinase 3.
    
0.905
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.