STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACLP00000008069Uncharacterized protein. (196 aa)    
Predicted Functional Partners:
ENSACLP00000014482
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.864
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.864
ENSACLP00000025549
CARD domain-containing protein.
  
  
 
0.805
ENSACLP00000025651
annotation not available
  
  
 
0.805
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.803
ENSACLP00000018312
Baculoviral IAP repeat containing 6.
   
 0.731
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
  0.632
ENSACLP00000035615
Uncharacterized protein.
    
 0.625
ENSACLP00000035628
Interleukin-1.
    
 0.625
ripk4
Receptor-interacting serine-threonine kinase 4.
    
  0.610
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.