| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSACLP00000001017 | LIAS | ENSACLP00000001017 | ENSACLP00000022826 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.861 |
| ENSACLP00000001017 | LOC113022645 | ENSACLP00000001017 | ENSACLP00000002363 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.823 |
| ENSACLP00000001017 | LOC113027474 | ENSACLP00000001017 | ENSACLP00000035690 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.823 |
| ENSACLP00000001017 | dlat | ENSACLP00000001017 | ENSACLP00000029847 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
| ENSACLP00000001017 | fasn | ENSACLP00000001017 | ENSACLP00000037597 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Coiled-coil domain containing 57. | 0.799 |
| ENSACLP00000001017 | lipt1 | ENSACLP00000001017 | ENSACLP00000008112 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Lipoyltransferase 1. | 0.919 |
| ENSACLP00000001017 | lipt2 | ENSACLP00000001017 | ENSACLP00000015010 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.565 |
| ENSACLP00000001017 | mecr | ENSACLP00000001017 | ENSACLP00000041247 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | Mitochondrial trans-2-enoyl-CoA reductase. | 0.537 |
| ENSACLP00000001017 | oxsm | ENSACLP00000001017 | ENSACLP00000025588 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.694 |
| LIAS | ENSACLP00000001017 | ENSACLP00000022826 | ENSACLP00000001017 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.861 |
| LIAS | LOC113022645 | ENSACLP00000022826 | ENSACLP00000002363 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.962 |
| LIAS | LOC113027474 | ENSACLP00000022826 | ENSACLP00000035690 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.962 |
| LIAS | dbt | ENSACLP00000022826 | ENSACLP00000029673 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.748 |
| LIAS | dlat | ENSACLP00000022826 | ENSACLP00000029847 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.902 |
| LIAS | lipt1 | ENSACLP00000022826 | ENSACLP00000008112 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Lipoyltransferase 1. | 0.975 |
| LIAS | lipt2 | ENSACLP00000022826 | ENSACLP00000015010 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.972 |
| LOC113022645 | ENSACLP00000001017 | ENSACLP00000002363 | ENSACLP00000001017 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.823 |
| LOC113022645 | LIAS | ENSACLP00000002363 | ENSACLP00000022826 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.962 |
| LOC113022645 | LOC113027474 | ENSACLP00000002363 | ENSACLP00000035690 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.915 |
| LOC113022645 | dbt | ENSACLP00000002363 | ENSACLP00000029673 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.829 |
