STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC113027103Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family. (563 aa)    
Predicted Functional Partners:
ENSACLP00000041285
Prostaglandin E synthase.
     
 0.902
ENSACLP00000000787
Prostaglandin E synthase 2-like; Belongs to the GST superfamily.
     
 0.898
LOC113033501
Prostaglandin-endoperoxide synthase 1.
   
 
 0.893
ENSACLP00000041483
Prostaglandin-endoperoxide synthase 1.
   
 
 0.893
ptges3
Prostaglandin E synthase 3a (cytosolic).
   
 
 0.887
LOC113022268
Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family.
     
 0.873
ptgs2
Prostaglandin-endoperoxide synthase 2b.
     
 0.872
prxl2b
Peroxiredoxin like 2B.
     
 0.860
med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.860
LOC113029073
Prostaglandin D2 synthase b, tandem duplicate 1; Belongs to the calycin superfamily. Lipocalin family.
     
 0.858
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.