Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
SETD2SET domain containing 2, histone lysine methyltransferase. (2605 aa)    
Predicted Functional Partners:
dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.989
ENSACLP00000029365
Lysine (K)-specific methyltransferase 2E.
   
 0.987
lrrc71
Ash1 (absent, small, or homeotic)-like (Drosophila).
   
 
 0.985
ENSACLP00000018302
Uncharacterized protein.
   
 0.978
setd1b
SET domain containing 1B, histone lysine methyltransferase a.
   
 0.978
setd1a
SET domain containing 1A, histone lysine methyltransferase.
   
 0.978
suv39h1
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
 0.973
ENSACLP00000017394
TFIIS N-terminal domain-containing protein.
   
 
 0.966
setd5
SET domain containing 5.
   
 
 0.965
ENSACLP00000029187
Uncharacterized protein.
   
 
 0.964
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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