Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hace1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (903 aa)    
Predicted Functional Partners:
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.957
RPS27A
Ribosomal protein S27a.
    
 0.952
ENSACLP00000009605
Ubiquitin B.
    
 0.930
LOC113030103
Uncharacterized protein.
    
 0.930
ambra1
Autophagy/beclin-1 regulator 1b.
    
 0.901
ENSACLP00000015402
Ubiquitin-like domain-containing protein.
    
 0.858
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.856
LOC113021021
Aly/REF export factor.
    
 
 0.828
LOC113023193
RRM domain-containing protein.
    
 
 0.828
eprs1
Glutamyl-prolyl-tRNA synthetase.
   
   0.819
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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