Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ikbkeInhibitor of nuclear factor kappa B kinase subunit epsilon. (818 aa)    
Predicted Functional Partners:
tank
TRAF family member-associated NFKB activator.
   
 0.994
LOC113019278
Interferon regulatory factor 3.
    
 0.993
sting1
Transmembrane protein 173.
   
 0.993
sqstm1
Sequestosome 1.
    
 0.989
optn
Optineurin.
    
 0.988
ENSACLP00000035197
SKICH domain-containing protein.
    
 0.984
LOC113024716
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.981
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.981
exoc2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
   
 0.980
tax1bp1
Tax1 (human T-cell leukemia virus type I) binding protein 1b.
    
 0.966
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
Server load: low (16%) [HD]