node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUH43606.1 | ubiB_2 | RUM4293_02501 | RUM4293_01811 | rpsU-divergently transcribed protein. | Putative ubiquinone biosynthesis protein UbiB. | 0.614 |
CUH43606.1 | ubiF | RUM4293_02501 | RUM4293_02805 | rpsU-divergently transcribed protein. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.563 |
CUH43606.1 | ubiG_2 | RUM4293_02501 | RUM4293_01827 | rpsU-divergently transcribed protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.526 |
CUH43606.1 | ubiH | RUM4293_02501 | RUM4293_01382 | rpsU-divergently transcribed protein. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.593 |
mutM | rpsT | RUM4293_01809 | RUM4293_01807 | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Hypothetical protein; Binds directly to 16S ribosomal RNA. | 0.577 |
mutM | ubiB_2 | RUM4293_01809 | RUM4293_01811 | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Putative ubiquinone biosynthesis protein UbiB. | 0.713 |
mutM | ubiE_5 | RUM4293_01809 | RUM4293_01810 | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.581 |
pasT | ubiA | RUM4293_00202 | RUM4293_02521 | Ribosome association toxin RatA. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.647 |
pasT | ubiB_2 | RUM4293_00202 | RUM4293_01811 | Ribosome association toxin RatA. | Putative ubiquinone biosynthesis protein UbiB. | 0.567 |
pasT | ubiG_2 | RUM4293_00202 | RUM4293_01827 | Ribosome association toxin RatA. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.717 |
pasT | ubiH | RUM4293_00202 | RUM4293_01382 | Ribosome association toxin RatA. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.426 |
rpsT | mutM | RUM4293_01807 | RUM4293_01809 | Hypothetical protein; Binds directly to 16S ribosomal RNA. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.577 |
rpsT | ubiB_2 | RUM4293_01807 | RUM4293_01811 | Hypothetical protein; Binds directly to 16S ribosomal RNA. | Putative ubiquinone biosynthesis protein UbiB. | 0.515 |
ubiA | pasT | RUM4293_02521 | RUM4293_00202 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Ribosome association toxin RatA. | 0.647 |
ubiA | ubiB_2 | RUM4293_02521 | RUM4293_01811 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Putative ubiquinone biosynthesis protein UbiB. | 0.499 |
ubiA | ubiE_5 | RUM4293_02521 | RUM4293_01810 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.622 |
ubiA | ubiF | RUM4293_02521 | RUM4293_02805 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. | 0.430 |
ubiA | ubiG_2 | RUM4293_02521 | RUM4293_01827 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.881 |
ubiA | ubiH | RUM4293_02521 | RUM4293_01382 | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.644 |
ubiB_2 | CUH43606.1 | RUM4293_01811 | RUM4293_02501 | Putative ubiquinone biosynthesis protein UbiB. | rpsU-divergently transcribed protein. | 0.614 |