STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A484C4U1Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (858 aa)    
Predicted Functional Partners:
A0A484CZF0
HMG box domain-containing protein.
   
 0.987
A0A484D400
PHD-type domain-containing protein.
    
 0.987
A0A484C3D2
Uncharacterized protein.
   
 0.976
A0A484C7I0
Uncharacterized protein.
   
 0.966
A0A484DK08
Uncharacterized protein.
   
 0.966
A0A484D509
HMG box domain-containing protein.
   
 0.940
A0A484CC57
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.938
A0A484CSR8
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.938
A0A484CEH1
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.934
A0A484CY90
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.932
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.