Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A484C505Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4113 aa)    
Predicted Functional Partners:
A0A484CVN9
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 0.999
A0A484CB59
VWFA domain-containing protein.
   
 0.998
A0A484CCM0
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.998
A0A484CMS3
Uncharacterized protein.
    
 0.997
A0A484BZ38
Uncharacterized protein.
    
 0.995
A0A484C3N5
DNA ligase.
    
 0.993
A0A484C8Y6
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 
 0.981
A0A484DKU8
BRCT domain-containing protein; Belongs to the DNA polymerase type-X family.
    
 0.971
A0A484DE15
Uncharacterized protein.
    
 
 0.967
A0A484DKS1
Non-specific serine/threonine protein kinase.
   
 0.961
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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