Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A484C571UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)    
Predicted Functional Partners:
A0A484DN91
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.986
A0A484CTX1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.982
A0A484D4S0
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.982
A0A484DJA5
Uncharacterized protein.
    
 0.982
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
  
 0.981
A0A484CME9
Uncharacterized protein.
   
 0.971
A0A484CE79
RBR-type E3 ubiquitin transferase.
    
 0.966
A0A484C650
Uncharacterized protein.
    
 0.965
A0A484CCQ2
Ubiquitin-like domain-containing protein.
   
 0.964
A0A484CKX6
RING-type domain-containing protein.
   
 0.962
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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