close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A484C675Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)    
Predicted Functional Partners:
A0A484D2F7
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
0.915
A0A484CUV7
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
  
 0.908
A0A484DCB6
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.898
A0A484DN25
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.871
A0A484D2W0
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.869
A0A484DAP3
Uncharacterized protein.
   
 0.868
A0A484CSL7
Uncharacterized protein.
     
 0.864
A0A484DGH4
Cytochrome b5 heme-binding domain-containing protein.
    
 0.863
A0A484DR65
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.859
A0A484CIR3
AB hydrolase-1 domain-containing protein.
   
 0.856
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
Server load: low (18%) [HD]