Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A484C675Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)    
Predicted Functional Partners:
A0A484CUV7
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
  
 0.973
A0A484D2F7
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
0.963
A0A484DCB6
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.956
A0A484D2W0
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
0.951
A0A484DN25
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
0.951
A0A484CK78
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.948
A0A484C5V2
Uncharacterized protein.
  
0.947
A0A484DK00
Uncharacterized protein.
  
0.947
A0A484CJ40
Uncharacterized protein.
  
 
 0.946
A0A484CZE2
Uncharacterized protein.
  
 
 0.936
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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