Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A484C847Uncharacterized protein. (463 aa)    
Predicted Functional Partners:
A0A484C5E1
Helicase C-terminal domain-containing protein.
   
 0.973
A0A484CB36
Helicase ATP-binding domain-containing protein.
   
 0.973
A0A484CLS0
Uncharacterized protein.
   
 0.961
A0A484DC07
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.946
A0A484C897
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
  
 0.940
A0A484CG57
DNA helicase; Belongs to the MCM family.
   
 0.924
A0A484CCD8
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.923
A0A484CBC0
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.922
A0A484CCH1
MCM domain-containing protein; Belongs to the MCM family.
   
 0.922
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.922
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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