Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
A0A484C940WD_REPEATS_REGION domain-containing protein. (637 aa)    
Predicted Functional Partners:
A0A484DIG2
Uncharacterized protein.
    
 
 0.846
A0A484C5H5
Uncharacterized protein.
    
 
 0.841
A0A484DHK6
Uncharacterized protein.
    
 
 0.840
A0A484DH82
FHA domain-containing protein.
   
 
 0.839
A0A484BZK0
Uncharacterized protein.
    
 
 0.830
A0A484DGH4
Cytochrome b5 heme-binding domain-containing protein.
    
   0.827
A0A484D538
CortBP2 domain-containing protein.
   
 
 0.809
A0A484DEP9
CortBP2 domain-containing protein.
   
 
 0.809
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
 
 0.792
A0A484DKK2
Protein kinase domain-containing protein.
   
  0.761
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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