MGME1 protein (Perca flavescens) - STRING interaction network

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MGME1

Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (351 aa)

Predicted Functional Partners:

A0A484C8X1

0.958

A0A484DIU5

0.870

A0A484CD45

0.744

A0A484C2I8

0.743

A0A484D244

0.733

A0A484CZD4

0.707

A0A484C5D5

0.706

FEN1

0.706

A0A484DFQ7

0.705

A0A484DPB3

0.705

Your Current Organism:

Perca flavescens

NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A484C2I8	A0A484D244	A0A484C2I8	A0A484D244	SF4 helicase domain-containing protein.	POLAc domain-containing protein.	0.960
A0A484C2I8	A0A484DPB3	A0A484C2I8	A0A484DPB3	SF4 helicase domain-containing protein.	Uncharacterized protein.	0.657
A0A484C2I8	FEN1	A0A484C2I8	A0A484C673	SF4 helicase domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.510
A0A484C2I8	MGME1	A0A484C2I8	A0A484CB72	SF4 helicase domain-containing protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.743
A0A484C5D5	FEN1	A0A484C5D5	A0A484C673	WW domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.778
A0A484C5D5	MGME1	A0A484C5D5	A0A484CB72	WW domain-containing protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.706
A0A484C8X1	MGME1	A0A484C8X1	A0A484CB72	ECSIT_Cterm domain-containing protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.958
A0A484CD45	A0A484DFQ7	A0A484CD45	A0A484DFQ7	Uncharacterized protein.	N2227 domain-containing protein.	0.832
A0A484CD45	MGME1	A0A484CD45	A0A484CB72	Uncharacterized protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.744
A0A484CZD4	MGME1	A0A484CZD4	A0A484CB72	Uncharacterized protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.707
A0A484D244	A0A484C2I8	A0A484D244	A0A484C2I8	POLAc domain-containing protein.	SF4 helicase domain-containing protein.	0.960
A0A484D244	A0A484DPB3	A0A484D244	A0A484DPB3	POLAc domain-containing protein.	Uncharacterized protein.	0.659
A0A484D244	FEN1	A0A484D244	A0A484C673	POLAc domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.684
A0A484D244	MGME1	A0A484D244	A0A484CB72	POLAc domain-containing protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.733
A0A484DFQ7	A0A484CD45	A0A484DFQ7	A0A484CD45	N2227 domain-containing protein.	Uncharacterized protein.	0.832
A0A484DFQ7	MGME1	A0A484DFQ7	A0A484CB72	N2227 domain-containing protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.705
A0A484DIU5	MGME1	A0A484DIU5	A0A484CB72	Peptidase_M3 domain-containing protein.	Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family.	0.870
A0A484DPB3	A0A484C2I8	A0A484DPB3	A0A484C2I8	Uncharacterized protein.	SF4 helicase domain-containing protein.	0.657
A0A484DPB3	A0A484D244	A0A484DPB3	A0A484D244	Uncharacterized protein.	POLAc domain-containing protein.	0.659
A0A484DPB3	FEN1	A0A484DPB3	A0A484C673	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.990

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