STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A484CB92S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (387 aa)    
Predicted Functional Partners:
A0A484C3V1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.971
A0A484CYJ6
Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.
  
 
 0.968
A0A484D2I7
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
  
 0.963
A0A484C809
S-adenosylmethionine decarboxylase proenzyme.
   
 
 0.955
A0A484CPG3
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
  
 0.954
A0A484CDZ9
Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.
  
 
 0.876
A0A484DAZ4
Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.
  
 
 0.876
A0A484DEN0
Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism.
  
 
 0.876
A7XLV2_PERFV
Betaine homocysteine S-methyltansferase; Involved in the regulation of homocysteine metabolism.
  
 
 0.876
A0A484D6U7
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.839
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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