Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
A0A484CBY2Fibroblast growth factor receptor. (859 aa)    
Predicted Functional Partners:
A0A484CM92
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
    
 0.984
A0A484CAJ8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.970
A0A484BZ43
Uncharacterized protein; Belongs to the heparin-binding growth factors family.
    
 0.967
A0A484DNG3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.960
A0A484DN10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.955
A0A484CEQ1
Uncharacterized protein.
    
 0.947
A0A484CXM0
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.936
A0A484CY57
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.936
A0A484DMI3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.936
A0A484DCH8
Uncharacterized protein; Belongs to the heparin-binding growth factors family.
    
 0.933
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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