Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LZTS2-2Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (785 aa)    
Predicted Functional Partners:
A0A484CL65
Uncharacterized protein.
   
  0.928
A0A484DA27
Uncharacterized protein.
   
  0.928
LZTS2
Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family.
  
  
 
0.902
A0A484DCB1
Uncharacterized protein.
    
   0.835
A0A484C4E3
Uncharacterized protein.
    
 0.751
A0A484DAI4
Protein kinase domain-containing protein.
    
   0.659
A0A484DJC2
Protein kinase domain-containing protein.
    
   0.659
A0A484CVU3
Uncharacterized protein.
    
 0.647
A0A484CW65
Uncharacterized protein.
    
 0.646
A0A484CNY6
Uncharacterized protein.
    
 0.590
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.