Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa)    
Predicted Functional Partners:
ELOVL6
Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...]
   
 
0.967
ELOVL7
Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...]
  
 
0.905
A0A484C4E8
Pyruvate carboxyltransferase domain-containing protein.
      
 0.894
A0A484DMN5
FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
      
 0.894
A0A484D3I4
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.850
A0A484DMW5
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.850
A0A484CS87
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.823
A0A484CKA3
FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
  
 0.703
A0A484CBE1
FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
  
 0.695
A0A484CFR3
FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
  
 0.695
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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