STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A484CD07Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (578 aa)    
Predicted Functional Partners:
A0A484D3G4
DHFR domain-containing protein.
    
 0.930
A0A484C8U6
Thymidylat_synt domain-containing protein.
     
 0.929
A0A484DBC7
Uncharacterized protein.
    
 0.914
A0A484DCL0
Uncharacterized protein.
    
 0.914
A0A484D2S7
Flavoprotein domain-containing protein.
    
 0.912
A0A484C5G1
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.909
A0A484CQ51
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.909
A0A484DDU6
Folate gamma-glutamyl hydrolase.
     
 0.906
A0A484DE77
Folate gamma-glutamyl hydrolase.
     
 0.906
A0A484DFD3
Uncharacterized protein.
    
 0.895
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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