STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A484D6C9Uncharacterized protein. (1097 aa)    
Predicted Functional Partners:
A0A484C6U9
Uncharacterized protein.
   
 
 0.638
A0A484CPB5
Uncharacterized protein.
   
 
 0.638
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
   
 
 0.638
A0A484D8R7
Uncharacterized protein.
   
 
 0.638
A0A484DIL2
Uncharacterized protein.
   
 
 0.638
A0A484DHQ5
Uncharacterized protein.
   
  
 0.626
A0A484CFF8
Uncharacterized protein.
   
  
 0.602
A0A484DL77
Uncharacterized protein.
   
  
 0.602
A0A484CPW6
Uncharacterized protein.
   
  
 0.536
A0A484D8C1
Uncharacterized protein.
   
  
 0.536
Your Current Organism:
Perca flavescens
NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.