ENSSAUP00010007366 protein (Sparus aurata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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Textmining

[Homology]

Score

ENSSAUP00010007366

annotation not available (117 aa)

Predicted Functional Partners:

ENSSAUP00010007280

0.540

ENSSAUP00010049901

0.534

ENSSAUP00010050380

0.534

lgr4

0.518

rxfp1

0.518

LGR5

0.518

ENSSAUP00010061128

0.518

LOC115566939

0.494

LOC115566937

0.494

ENSSAUP00010036849

0.491

Your Current Organism:

Sparus aurata

NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSAUP00010007280	ENSSAUP00010007366	ENSSAUP00010007280	ENSSAUP00010007366	annotation not available	annotation not available	0.540
ENSSAUP00010007366	ENSSAUP00010007280	ENSSAUP00010007366	ENSSAUP00010007280	annotation not available	annotation not available	0.540
ENSSAUP00010007366	ENSSAUP00010036849	ENSSAUP00010007366	ENSSAUP00010036849	annotation not available	annotation not available	0.491
ENSSAUP00010007366	ENSSAUP00010049901	ENSSAUP00010007366	ENSSAUP00010049901	annotation not available	annotation not available	0.534
ENSSAUP00010007366	ENSSAUP00010050380	ENSSAUP00010007366	ENSSAUP00010050380	annotation not available	annotation not available	0.534
ENSSAUP00010007366	ENSSAUP00010061128	ENSSAUP00010007366	ENSSAUP00010061128	annotation not available	Relaxin family peptide receptor 2a.	0.518
ENSSAUP00010007366	LGR5	ENSSAUP00010007366	ENSSAUP00010035010	annotation not available	Leucine rich repeat containing G protein-coupled receptor 5.	0.518
ENSSAUP00010007366	LOC115566937	ENSSAUP00010007366	ENSSAUP00010016137	annotation not available	H-2 class II histocompatibility antigen, A-U alpha chain-like.	0.494
ENSSAUP00010007366	LOC115566939	ENSSAUP00010007366	ENSSAUP00010016126	annotation not available	H-2 class II histocompatibility antigen, A-U alpha chain-like.	0.494
ENSSAUP00010007366	lgr4	ENSSAUP00010007366	ENSSAUP00010004722	annotation not available	Leucine rich repeat containing G protein-coupled receptor 4.	0.518
ENSSAUP00010007366	rxfp1	ENSSAUP00010007366	ENSSAUP00010025539	annotation not available	Relaxin family peptide receptor 1.	0.518
ENSSAUP00010036849	ENSSAUP00010007366	ENSSAUP00010036849	ENSSAUP00010007366	annotation not available	annotation not available	0.491
ENSSAUP00010036849	LOC115566937	ENSSAUP00010036849	ENSSAUP00010016137	annotation not available	H-2 class II histocompatibility antigen, A-U alpha chain-like.	0.875
ENSSAUP00010036849	LOC115566939	ENSSAUP00010036849	ENSSAUP00010016126	annotation not available	H-2 class II histocompatibility antigen, A-U alpha chain-like.	0.878
ENSSAUP00010049901	ENSSAUP00010007366	ENSSAUP00010049901	ENSSAUP00010007366	annotation not available	annotation not available	0.534
ENSSAUP00010050380	ENSSAUP00010007366	ENSSAUP00010050380	ENSSAUP00010007366	annotation not available	annotation not available	0.534
ENSSAUP00010061128	ENSSAUP00010007366	ENSSAUP00010061128	ENSSAUP00010007366	Relaxin family peptide receptor 2a.	annotation not available	0.518
ENSSAUP00010061128	LGR5	ENSSAUP00010061128	ENSSAUP00010035010	Relaxin family peptide receptor 2a.	Leucine rich repeat containing G protein-coupled receptor 5.	0.567
ENSSAUP00010061128	lgr4	ENSSAUP00010061128	ENSSAUP00010004722	Relaxin family peptide receptor 2a.	Leucine rich repeat containing G protein-coupled receptor 4.	0.567
ENSSAUP00010061128	rxfp1	ENSSAUP00010061128	ENSSAUP00010025539	Relaxin family peptide receptor 2a.	Relaxin family peptide receptor 1.	0.744

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

15

PPI enrichment p-value:

4.66e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006166

Purine ribonucleoside salvage

2 of 4

2.65

1.0

0.0155

GO:0055086

Nucleobase-containing small molecule metabolic process

5 of 210

1.32

0.89

0.0074

GO:0072522

Purine-containing compound biosynthetic process

3 of 68

1.59

0.85

0.0182

GO:0009168

Purine ribonucleoside monophosphate biosynthetic process

2 of 17

2.02

0.83

0.0280

GO:1901137

Carbohydrate derivative biosynthetic process

4 of 222

1.2

0.72

0.0182

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13127

Metabolism of nucleotides, and Purine nucleoside catabolic process

7 of 78

1.9

3.59

1.73e-09

CL:13128

Nucleoside monophosphate metabolic process, and Nucleoside-triphosphate diphosphatase activity

5 of 48

1.96

2.75

1.06e-06

CL:13129

Purine ribonucleoside monophosphate biosynthesis, and Adenosine deaminase domain

3 of 24

2.04

1.47

0.0014

CL:13239

Cytidine and deoxycytidylate deaminase zinc-binding region, and Bacterial bifunctional deaminase-reductase, C-terminal

2 of 5

2.55

1.13

0.0088

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

3 of 98

1.43

0.75

0.0250

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00383

Cytidine and deoxycytidylate deaminase zinc-binding region

2 of 7

2.4

0.76

0.0416

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