STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pola1DNA polymerase alpha 1, catalytic subunit. (1522 aa)    
Predicted Functional Partners:
ENSSAUP00010029055
DNA primase subunit 1.
   
 0.999
pola2
DNA polymerase alpha 2, accessory subunit.
   
 0.999
prim2
DNA primase subunit 2.
   
 0.999
wdhd1
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.998
ENSSAUP00010020937
Polymerase (DNA directed), epsilon 2.
   
 0.997
ENSSAUP00010059421
Polymerase (DNA directed), epsilon.
   
 0.997
pcna
Proliferating cell nuclear antigen.
  
 0.996
mcm4
Minichromosome maintenance complex component 4.
   
 0.996
mcm2
Minichromosome maintenance complex component 2.
   
 0.995
mcm3
Minichromosome maintenance complex component 3.
   
 0.993
Your Current Organism:
Sparus aurata
NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.