STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sos2SOS Ras/Rho guanine nucleotide exchange factor 2. (1330 aa)    
Predicted Functional Partners:
LOC115576166
Growth factor receptor-bound protein 2.
   
 0.978
ENSSAUP00010023061
annotation not available
   
 0.978
egfr
Epidermal growth factor receptor.
    
 0.932
ENSSAUP00010058507
annotation not available
    
 0.932
hras
HRas proto-oncogene, GTPase.
   
 0.925
ptpn11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.922
ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.922
LOC115585499
Tyrosine-protein phosphatase non-receptor type 11-like.
    
 0.922
kras
KRAS proto-oncogene, GTPase.
   
 0.911
LOC115575058
GTPase HRas-like.
   
 0.911
Your Current Organism:
Sparus aurata
NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.