STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
numbNUMB endocytic adaptor protein. (651 aa)    
Predicted Functional Partners:
LOC115591296
Neurogenic locus notch homolog protein 2-like.
    
 0.935
ap2a1
Adaptor related protein complex 2 subunit alpha 1.
    
 0.928
LOC115575327
Neurogenic locus notch homolog protein 2-like.
    
 0.909
LOC115592856
Neurogenic locus notch homolog protein 1-like.
    
 0.903
notch1
Notch receptor 1.
    
 0.903
gak
Cyclin G associated kinase.
   
 
 0.859
LOC115597499
Numb-like protein.
  
  
 
0.851
mdm2
MDM2 proto-oncogene.
    
 
 0.809
LOC115583693
E3 ubiquitin-protein ligase Itchy-like.
    
 0.805
LOC115585057
E3 ubiquitin-protein ligase Itchy-like.
    
 0.805
Your Current Organism:
Sparus aurata
NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.