STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hecw1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1657 aa)    
Predicted Functional Partners:
ENSSAUP00010062713
Ribosomal protein S27a.
    
 0.886
ENSSAUP00010019090
annotation not available
    
 0.877
ENSSAUP00010062031
Ubiquitin B.
    
 0.877
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.844
LOC115572968
ubiquitin-60S ribosomal protein L40-like.
    
 0.834
ENSSAUP00010058412
TNF receptor-associated factor 6.
    
 0.826
ENSSAUP00010029875
Proteasome 26S subunit, non-ATPase 4a.
    
 0.807
LOC115568133
26S proteasome non-ATPase regulatory subunit 4-like.
    
 0.807
LOC115579700
Mothers against decapentaplegic homolog 6-like.
    
 0.801
smad6
SMAD family member 6.
    
 0.801
Your Current Organism:
Sparus aurata
NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.