STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN29629.1Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (113 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.946
KRN29516.1
S-adenosyl-L-methionine-dependent methyltransferase.
  
     0.759
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
  
  
 0.715
KRN27453.1
Hypothetical protein; Belongs to the UPF0297 family.
 
     0.703
KRN29473.1
Fibronectin binding protein A.
  
     0.699
ftsY
Signal recognition particle docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
  
  
 0.698
rnc
Rnc protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
 
    0.695
KRN29664.1
Hypothetical protein.
 
     0.671
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
    0.668
rpsP
Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
    0.630
Your Current Organism:
Lactobacillus selangorensis
NCBI taxonomy Id: 81857
Other names: ATCC BAA-66, CCUG 43347, CIP 106482, DSM 13344, L. selangorensis, LMG 17710, LMG:17710, Lactobacillus selangorensis (Leisner et al. 2000) Haakensen et al. 2011, Lactobacillus sp. LMG17710, Paralactobacillus selangorensis, Paralactobacillus selangorensis Leisner et al. 2000, bacterium LMG17714
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.