STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN28883.1Ribonuclease hi; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (155 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.954
topA
topA protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. [...]
   
 
 0.861
KRN28456.1
DNA topoisomerase III.
   
 
 0.861
rnhB
Ribonuclease HII family protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.848
KRN29218.1
Ssb protein.
   
 
 0.816
KRN28621.1
Single-strand DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.816
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
   
   0.707
KRN29440.1
ATP-dependent DNA helicase, RecQ family protein.
  
 
 0.646
KRN29483.1
Hypothetical protein.
  
  
  0.642
KRN29567.1
recJ protein.
   
 
 0.610
Your Current Organism:
Lactobacillus selangorensis
NCBI taxonomy Id: 81857
Other names: ATCC BAA-66, CCUG 43347, CIP 106482, DSM 13344, L. selangorensis, LMG 17710, LMG:17710, Lactobacillus selangorensis (Leisner et al. 2000) Haakensen et al. 2011, Lactobacillus sp. LMG17710, Paralactobacillus selangorensis, Paralactobacillus selangorensis Leisner et al. 2000, bacterium LMG17714
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