Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TgfbiTransforming growth factor, beta-induced. (679 aa)    
Predicted Functional Partners:
lum
LRRNT domain-containing protein.
   
  
 0.599
ENSLCAP00010010443
Collagen, type VI, alpha 1.
   
 
 0.582
Ndufs2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
    
 
 0.572
kynu
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
      
 0.560
prrx1
Uncharacterized protein.
   
  
 0.508
ND4
Oxidored_q5_N domain-containing protein.
    
 0.492
ENSLCAP00010006479
Proton_antipo_M domain-containing protein.
    
 0.492
Ggcx
Gamma-glutamyl carboxylase.
   
  
 0.491
ENSLCAP00010013697
Secreted protein, acidic, cysteine-rich (osteonectin).
   
 
 0.483
ENSLCAP00010021728
BHLH domain-containing protein.
      
 0.482
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
Server load: low (20%) [HD]