rest protein (Lates calcarifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rest

Uncharacterized protein. (997 aa)

Predicted Functional Partners:

ENSLCAP00010040277

0.886

rcor1

0.870

rcor2

0.789

rcor3

0.789

Sin3a

0.677

ENSLCAP00010040886

0.677

sin3b

0.677

Phf21a

0.655

Htt

0.618

hdac1

0.593

Your Current Organism:

Lates calcarifer

NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLCAP00010040277	Phf21a	ENSLCAP00010040277	ENSLCAP00010001348	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.970
ENSLCAP00010040277	hdac1	ENSLCAP00010040277	ENSLCAP00010009699	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.874
ENSLCAP00010040277	rcor1	ENSLCAP00010040277	ENSLCAP00010048300	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.969
ENSLCAP00010040277	rcor2	ENSLCAP00010040277	ENSLCAP00010039130	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.947
ENSLCAP00010040277	rcor3	ENSLCAP00010040277	ENSLCAP00010055435	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.947
ENSLCAP00010040277	rest	ENSLCAP00010040277	ENSLCAP00010009076	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	Uncharacterized protein.	0.886
ENSLCAP00010040886	hdac1	ENSLCAP00010040886	ENSLCAP00010009699	SIN3 transcription regulator family member Ab.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.818
ENSLCAP00010040886	rest	ENSLCAP00010040886	ENSLCAP00010009076	SIN3 transcription regulator family member Ab.	Uncharacterized protein.	0.677
Htt	rest	ENSLCAP00010045630	ENSLCAP00010009076	Huntingtin.	Uncharacterized protein.	0.618
Phf21a	ENSLCAP00010040277	ENSLCAP00010001348	ENSLCAP00010040277	Uncharacterized protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.970
Phf21a	hdac1	ENSLCAP00010001348	ENSLCAP00010009699	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.711
Phf21a	rcor1	ENSLCAP00010001348	ENSLCAP00010048300	Uncharacterized protein.	Uncharacterized protein.	0.803
Phf21a	rcor2	ENSLCAP00010001348	ENSLCAP00010039130	Uncharacterized protein.	Uncharacterized protein.	0.803
Phf21a	rcor3	ENSLCAP00010001348	ENSLCAP00010055435	Uncharacterized protein.	Uncharacterized protein.	0.803
Phf21a	rest	ENSLCAP00010001348	ENSLCAP00010009076	Uncharacterized protein.	Uncharacterized protein.	0.655
Sin3a	hdac1	ENSLCAP00010013907	ENSLCAP00010009699	SIN3 transcription regulator family member Aa.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.818
Sin3a	rest	ENSLCAP00010013907	ENSLCAP00010009076	SIN3 transcription regulator family member Aa.	Uncharacterized protein.	0.677
hdac1	ENSLCAP00010040277	ENSLCAP00010009699	ENSLCAP00010040277	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.874
hdac1	ENSLCAP00010040886	ENSLCAP00010009699	ENSLCAP00010040886	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	SIN3 transcription regulator family member Ab.	0.818
hdac1	Phf21a	ENSLCAP00010009699	ENSLCAP00010001348	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.711