STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSLCAP00010011267Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (72 aa)    
Predicted Functional Partners:
LOC108900731
F-box domain-containing protein.
   
 0.945
skp1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.918
ccna1
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.881
ccna2
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.881
cul1
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.864
Ccnf
Cyclin F; Belongs to the cyclin family.
   
 0.766
ENSLCAP00010021685
Cyclin J; Belongs to the cyclin family.
   
 0.766
LOC108882948
Uncharacterized protein; Belongs to the cyclin family.
   
 0.766
cdk2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.756
Cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.756
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.