STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mex3bRING-type domain-containing protein. (542 aa)    
Predicted Functional Partners:
snupn
IBB domain-containing protein.
    
 
 0.621
ENSLCAP00010037926
Protein kinase domain-containing protein.
    
 0.609
dcp1a
mRNA_decap_C domain-containing protein.
   
 
 0.487
ENSLCAP00010013945
Tetratricopeptide repeat domain 9B.
    
 0.479
ift81
IFT81_CH domain-containing protein.
    
 0.472
ENSLCAP00010035657
Iodotyrosine deiodinase.
      
 0.469
bloc1s1
Uncharacterized protein.
     
 0.466
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
 0.453
ift22
Uncharacterized protein.
    
 0.443
ENSLCAP00010026700
Intraflagellar transport 88 homolog.
   
 0.437
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.