STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chd1Uncharacterized protein. (1797 aa)    
Predicted Functional Partners:
ENSLCAP00010023916
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.708
supt16h
Uncharacterized protein.
   
 
 0.702
ENSLCAP00010011538
Translocase of outer mitochondrial membrane 20.
   
 0.688
ENSLCAP00010059212
AT rich interactive domain 4A (RBP1-like).
   
 0.688
Actr5
ARP5 actin related protein 5 homolog; Belongs to the actin family.
    
 0.673
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.673
polr2c
RPOLD domain-containing protein.
   
 0.665
ino80c
YL1_C domain-containing protein.
    
 0.651
Supt5h
Transcription elongation factor SPT5.
   
 
 0.646
fancm
Uncharacterized protein.
    
0.641
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.