STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC108882682Uncharacterized protein. (894 aa)    
Predicted Functional Partners:
skp1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.902
cul1
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.833
rbx1
RING-type domain-containing protein.
    
 0.667
CUL3
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.654
LOC108886600
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.654
Nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.580
Cul2
Cullin 2; Belongs to the cullin family.
     
 0.568
ENSLCAP00010000673
Ubiquitin-like domain-containing protein.
    
 0.532
ENSLCAP00010014495
Ubiquitin-like domain-containing protein.
    
 0.532
UBA3
E2_bind domain-containing protein.
    
 0.532
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.