STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (305 aa)    
Predicted Functional Partners:
nadsyn1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.947
nampt
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.925
LOC108873533
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.920
nudt12
Uncharacterized protein.
    
 0.916
ENSLCAP00010030729
Uncharacterized protein.
     
 0.906
ENSLCAP00010030763
Uncharacterized protein.
     
 0.906
LOC108887893
Uncharacterized protein.
   
 
 0.902
ENSLCAP00010006425
Nicotinamide nucleotide transhydrogenase.
   
 
 0.902
LOC108887580
Uncharacterized protein.
    
  0.900
LOC108873497
Uncharacterized protein.
    
  0.900
Your Current Organism:
Lates calcarifer
NCBI taxonomy Id: 8187
Other names: Asian seabass, Holocentrus calcarifer, L. calcarifer, barramundi, barramundi perch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.