node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CUQ19935.1 | hisB | ERS852554_03380 | ERS852554_02242 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.931 |
CUQ19935.1 | hisC_1 | ERS852554_03380 | ERS852554_02241 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.909 |
CUQ19935.1 | hisC_2 | ERS852554_03380 | ERS852554_02957 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.921 |
CUQ19935.1 | hisD | ERS852554_03380 | ERS852554_02240 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.922 |
CUQ19935.1 | hisE | ERS852554_03380 | ERS852554_03526 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | phosphoribosyl-AMP cyclohydrolase%3B phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.601 |
CUQ19935.1 | hisK | ERS852554_03380 | ERS852554_02658 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol-phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.927 |
hisB | CUQ19935.1 | ERS852554_02242 | ERS852554_03380 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.931 |
hisB | hisC_1 | ERS852554_02242 | ERS852554_02241 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.999 |
hisB | hisC_2 | ERS852554_02242 | ERS852554_02957 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.998 |
hisB | hisD | ERS852554_02242 | ERS852554_02240 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
hisB | hisE | ERS852554_02242 | ERS852554_03526 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | phosphoribosyl-AMP cyclohydrolase%3B phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
hisB | hisF | ERS852554_02242 | ERS852554_03525 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
hisB | hisG | ERS852554_02242 | ERS852554_02239 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.996 |
hisB | hisH | ERS852554_02242 | ERS852554_03523 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
hisB | hisK | ERS852554_02242 | ERS852554_02658 | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Histidinol-phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.931 |
hisC_1 | CUQ19935.1 | ERS852554_02241 | ERS852554_03380 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.909 |
hisC_1 | hisB | ERS852554_02241 | ERS852554_02242 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Putative histidine biosynthesis bifunctional protein; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.999 |
hisC_1 | hisC_2 | ERS852554_02241 | ERS852554_02957 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.924 |
hisC_1 | hisD | ERS852554_02241 | ERS852554_02240 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.997 |
hisC_1 | hisE | ERS852554_02241 | ERS852554_03526 | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | phosphoribosyl-AMP cyclohydrolase%3B phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.991 |