STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUQ00954.1Uncharacterised protein. (412 aa)    
Predicted Functional Partners:
CUQ00977.1
Uncharacterised protein.
       0.782
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.454
parE
DNA topoisomerase type IIA subunit B region 2 domain protein.
   
 
 0.454
nlpD_1
Peptidase M23.
   
 
 0.429
nlpD_3
Peptidase M23.
   
 
 0.429
CUP43013.1
Peptidoglycan-binding lysin domain protein.
   
 
 0.426
mltD_2
Lytic transglycosylase catalytic.
   
 
 0.424
CUQ11580.1
Lipoprotein.
   
   0.407
Your Current Organism:
Bacteroides uniformis
NCBI taxonomy Id: 820
Other names: ATCC 8492, B. uniformis, CCUG 4942, CIP 103695, DSM 6597, JCM 5828, NCTC 13054
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.