STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
KXG90826.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (429 aa)    
Predicted Functional Partners:
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
    
 0.957
coaX
Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
 
 0.948
KXG89411.1
Aminotransferase, class I/II; KEGG: ols:Olsu_0095 2.7e-126 class I and II aminotransferase; K11358 aspartate aminotransferase; Psort location: Cytoplasmic, score: 7.50.
  
  0.945
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.917
KXG90804.1
Cysteine synthase A; KEGG: gvh:HMPREF9231_0553 2.2e-149 cysK; cysteine synthase A K01738; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.903
KXG90855.1
Aminotransferase, class I/II; KEGG: gva:HMPREF0424_1311 1.4e-200 aminotransferase AlaT K14260; Psort location: Cytoplasmic, score: 7.50.
  
  0.867
KXG90828.1
Aminotransferase, class V; KEGG: ols:Olsu_0922 7.7e-99 cysteine desulfurase K04487; Psort location: Cytoplasmic, score: 9.97.
  
  0.829
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
 
 0.822
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.822
KXG90829.1
KEGG: ols:Olsu_0921 6.4e-63 ribulose-5-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50; Belongs to the ribulose-phosphate 3-epimerase family.
   
   0.740
Your Current Organism:
Atopobium vaginae
NCBI taxonomy Id: 82135
Other names: A. vaginae, ATCC BAA-55, ATCC:BAA 55, ATCC:BAA:55, CCUG 38953, CIP 106431, DSM 15829, NCTC 13935
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