node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXG88502.1 | KXG88514.1 | HMPREF3232_01396 | HMPREF3232_01408 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.970 |
KXG88502.1 | KXG88889.1 | HMPREF3232_01396 | HMPREF3232_01199 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.886 |
KXG88502.1 | KXG90744.1 | HMPREF3232_01396 | HMPREF3232_00415 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: mml:MLC_4920 1.6e-15 recD; exodeoxyribonuclease V subunit alpha; K03581 exodeoxyribonuclease V alpha subunit. | 0.768 |
KXG88502.1 | KXG91086.1 | HMPREF3232_01396 | HMPREF3232_00192 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | KEGG: ols:Olsu_0735 7.8e-232 exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50. | 0.965 |
KXG88502.1 | polA | HMPREF3232_01396 | HMPREF3232_00588 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.991 |
KXG88502.1 | recA | HMPREF3232_01396 | HMPREF3232_00079 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.889 |
KXG88502.1 | topA | HMPREF3232_01396 | HMPREF3232_01187 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.959 |
KXG88502.1 | truB | HMPREF3232_01396 | HMPREF3232_00514 | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.823 |
KXG88514.1 | KXG88502.1 | HMPREF3232_01408 | HMPREF3232_01396 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | 0.970 |
KXG88514.1 | KXG88889.1 | HMPREF3232_01408 | HMPREF3232_01199 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.854 |
KXG88514.1 | KXG90744.1 | HMPREF3232_01408 | HMPREF3232_00415 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; KEGG: mml:MLC_4920 1.6e-15 recD; exodeoxyribonuclease V subunit alpha; K03581 exodeoxyribonuclease V alpha subunit. | 0.819 |
KXG88514.1 | KXG91086.1 | HMPREF3232_01408 | HMPREF3232_00192 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ols:Olsu_0735 7.8e-232 exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50. | 0.957 |
KXG88514.1 | polA | HMPREF3232_01408 | HMPREF3232_00588 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
KXG88514.1 | recA | HMPREF3232_01408 | HMPREF3232_00079 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.948 |
KXG88514.1 | topA | HMPREF3232_01408 | HMPREF3232_01187 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.819 |
KXG88889.1 | KXG88502.1 | HMPREF3232_01199 | HMPREF3232_01396 | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97. | 0.886 |
KXG88889.1 | KXG88514.1 | HMPREF3232_01199 | HMPREF3232_01408 | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.854 |
KXG88889.1 | KXG89578.1 | HMPREF3232_01199 | HMPREF3232_00852 | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | UvrD/REP helicase; KEGG: kol:Kole_1028 4.6e-45 Exodeoxyribonuclease V; Psort location: Cytoplasmic, score: 9.97; Belongs to the helicase family. UvrD subfamily. | 0.681 |
KXG88889.1 | KXG90744.1 | HMPREF3232_01199 | HMPREF3232_00415 | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: mml:MLC_4920 1.6e-15 recD; exodeoxyribonuclease V subunit alpha; K03581 exodeoxyribonuclease V alpha subunit. | 0.766 |
KXG88889.1 | KXG90745.1 | HMPREF3232_01199 | HMPREF3232_00416 | Putative ATP-dependent DNA helicase PcrA; KEGG: ols:Olsu_1470 1.8e-273 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | KEGG: cff:CFF8240_1393 8.9e-192 restriction and modification enzyme CjeI; K01154 type I restriction enzyme, S subunit; Psort location: Cytoplasmic, score: 7.50. | 0.475 |