KXG89319.1 protein (Atopobium vaginae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KXG89319.1

Hypothetical protein. (45 aa)

Predicted Functional Partners:

KXG89320.1

0.693

KXG89321.1

0.693

KXG89322.1

0.693

KXG89323.1

0.548

KXG89318.1

0.527

KXG89317.1

0.454

Your Current Organism:

Atopobium vaginae

NCBI taxonomy Id: 82135
Other names: A. vaginae, ATCC BAA-55, ATCC:BAA 55, ATCC:BAA:55, CCUG 38953, CIP 106431, DSM 15829, NCTC 13935

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KXG89317.1	KXG89318.1	HMPREF3232_00880	HMPREF3232_00881	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	0.655
KXG89317.1	KXG89319.1	HMPREF3232_00880	HMPREF3232_00882	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	Hypothetical protein.	0.454
KXG89317.1	KXG89320.1	HMPREF3232_00880	HMPREF3232_00883	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	KEGG: ssa:SSA_0049 1.4e-131 dihydroxyacetone kinase subunit DhaK K05878; Psort location: Cytoplasmic, score: 7.50.	0.477
KXG89317.1	KXG89321.1	HMPREF3232_00880	HMPREF3232_00884	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	KEGG: spv:SPH_1291 4.5e-55 dihydroxyacetone kinase, L subunit K05879; Psort location: Cytoplasmic, score: 7.50.	0.996
KXG89317.1	KXG89322.1	HMPREF3232_00880	HMPREF3232_00885	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	KEGG: llk:LLKF_0247 1.6e-27 dhaM; PTS-dependent dihydroxyacetone kinase phosphotransferase subunit; Psort location: Cytoplasmic, score: 7.50.	0.983
KXG89317.1	KXG89323.1	HMPREF3232_00880	HMPREF3232_00886	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	Channel protein, MIP family; KEGG: hiq:CGSHiGG_06740 3.0e-26 glpQ; glycerophosphodiester phosphodiesterase K02440; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.461
KXG89318.1	KXG89317.1	HMPREF3232_00881	HMPREF3232_00880	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	0.655
KXG89318.1	KXG89319.1	HMPREF3232_00881	HMPREF3232_00882	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	Hypothetical protein.	0.527
KXG89318.1	KXG89320.1	HMPREF3232_00881	HMPREF3232_00883	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	KEGG: ssa:SSA_0049 1.4e-131 dihydroxyacetone kinase subunit DhaK K05878; Psort location: Cytoplasmic, score: 7.50.	0.477
KXG89318.1	KXG89321.1	HMPREF3232_00881	HMPREF3232_00884	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	KEGG: spv:SPH_1291 4.5e-55 dihydroxyacetone kinase, L subunit K05879; Psort location: Cytoplasmic, score: 7.50.	0.477
KXG89318.1	KXG89322.1	HMPREF3232_00881	HMPREF3232_00885	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	KEGG: llk:LLKF_0247 1.6e-27 dhaM; PTS-dependent dihydroxyacetone kinase phosphotransferase subunit; Psort location: Cytoplasmic, score: 7.50.	0.600
KXG89318.1	KXG89323.1	HMPREF3232_00881	HMPREF3232_00886	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	Channel protein, MIP family; KEGG: hiq:CGSHiGG_06740 3.0e-26 glpQ; glycerophosphodiester phosphodiesterase K02440; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.402
KXG89319.1	KXG89317.1	HMPREF3232_00882	HMPREF3232_00880	Hypothetical protein.	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	0.454
KXG89319.1	KXG89318.1	HMPREF3232_00882	HMPREF3232_00881	Hypothetical protein.	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	0.527
KXG89319.1	KXG89320.1	HMPREF3232_00882	HMPREF3232_00883	Hypothetical protein.	KEGG: ssa:SSA_0049 1.4e-131 dihydroxyacetone kinase subunit DhaK K05878; Psort location: Cytoplasmic, score: 7.50.	0.693
KXG89319.1	KXG89321.1	HMPREF3232_00882	HMPREF3232_00884	Hypothetical protein.	KEGG: spv:SPH_1291 4.5e-55 dihydroxyacetone kinase, L subunit K05879; Psort location: Cytoplasmic, score: 7.50.	0.693
KXG89319.1	KXG89322.1	HMPREF3232_00882	HMPREF3232_00885	Hypothetical protein.	KEGG: llk:LLKF_0247 1.6e-27 dhaM; PTS-dependent dihydroxyacetone kinase phosphotransferase subunit; Psort location: Cytoplasmic, score: 7.50.	0.693
KXG89319.1	KXG89323.1	HMPREF3232_00882	HMPREF3232_00886	Hypothetical protein.	Channel protein, MIP family; KEGG: hiq:CGSHiGG_06740 3.0e-26 glpQ; glycerophosphodiester phosphodiesterase K02440; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.548
KXG89320.1	KXG89317.1	HMPREF3232_00883	HMPREF3232_00880	KEGG: ssa:SSA_0049 1.4e-131 dihydroxyacetone kinase subunit DhaK K05878; Psort location: Cytoplasmic, score: 7.50.	Putative dihydroxyacetone kinase DhaK1b subunit; KEGG: sds:SDEG_0554 2.6e-89 DhaKLM operon coactivator DhaQ K00863; Psort location: Cytoplasmic, score: 7.50.	0.477
KXG89320.1	KXG89318.1	HMPREF3232_00883	HMPREF3232_00881	KEGG: ssa:SSA_0049 1.4e-131 dihydroxyacetone kinase subunit DhaK K05878; Psort location: Cytoplasmic, score: 7.50.	Putative dihydroxyacetone kinase regulator; Psort location: Cytoplasmic, score: 7.50.	0.477

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.949

expected number of edges:

10

PPI enrichment p-value:

6.12e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0098930

Axonal transport

5 of 32

2.37

3.67

5.68e-08

GO:0047497

Mitochondrion transport along microtubule

4 of 12

2.7

3.6

1.89e-07

GO:0006607

NLS-bearing protein import into nucleus

4 of 16

2.58

3.41

3.47e-07

GO:0010970

Transport along microtubule

6 of 110

1.92

3.05

1.03e-07

GO:0000413

Protein peptidyl-prolyl isomerization

4 of 29

2.32

2.87

2.53e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0061665

SUMO ligase activity

4 of 13

2.67

3.31

6.55e-07

GO:0008574

Plus-end-directed microtubule motor activity

2 of 11

2.44

1.02

0.0137

GO:0031267

Small GTPase binding

4 of 230

1.42

0.89

0.0104

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044614

Nuclear pore cytoplasmic filaments

4 of 6

3.0

4.11

2.87e-08

GO:0005642

Annulate lamellae

4 of 7

2.94

4.09

2.87e-08

GO:0106068

SUMO ligase complex

4 of 11

2.74

3.97

3.74e-08

GO:0042405

Nuclear inclusion body

4 of 11

2.74

3.97

3.74e-08

GO:0044615

Nuclear pore nuclear basket

4 of 13

2.67

3.89

4.65e-08

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15666

Establishment of mitochondrion localization, and CH-like domain in sperm protein

3 of 11

2.61

1.92

0.00029

CL:5958

Transport of Mature mRNA Derived from an Intronless Transcript

3 of 29

2.19

1.58

0.00098

CL:16207

RHO GTPases activate KTN1

2 of 5

2.78

1.33

0.0039

CL:15669

MIRO domain, and HAP1, N-terminal

2 of 5

2.78

1.33

0.0039

CL:5999

Mixed, incl. Nuclear pore central transport channel, and Nuclear pore cytoplasmic filaments

2 of 7

2.64

1.25

0.0052

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-3301854

Nuclear Pore Complex (NPC) Disassembly

4 of 41

2.17

2.56

7.94e-06

MAP-159231

Transport of Mature mRNA Derived from an Intronless Transcript

4 of 40

2.18

2.56

7.94e-06

MAP-159227

Transport of the SLBP independent Mature mRNA

4 of 41

2.17

2.56

7.94e-06

MAP-159234

Transport of Mature mRNAs Derived from Intronless Transcripts

4 of 44

2.14

2.54

7.94e-06

MAP-159230

Transport of the SLBP Dependant Mature mRNA

4 of 43

2.15

2.54

7.94e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044614

Nuclear pore cytoplasmic filaments

4 of 5

3.08

4.21

2.01e-08

GOCC:0031967

Organelle envelope

6 of 427

1.33

1.42

6.42e-05

GOCC:0043229

Intracellular organelle

11 of 6905

0.38

0.29

0.0165

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00160

Ran-binding domain

2 of 8

2.58

1.04

0.0130

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About