node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXG88456.1 | KXG90278.1 | HMPREF3232_01344 | HMPREF3232_00711 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.999 |
KXG88456.1 | ddl | HMPREF3232_01344 | HMPREF3232_01397 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.819 |
KXG88456.1 | glmU | HMPREF3232_01344 | HMPREF3232_01231 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.580 |
KXG88456.1 | mraY | HMPREF3232_01344 | HMPREF3232_00712 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.908 |
KXG88456.1 | murA | HMPREF3232_01344 | HMPREF3232_00952 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.788 |
KXG88456.1 | murB | HMPREF3232_01344 | HMPREF3232_01222 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.841 |
KXG88456.1 | murC | HMPREF3232_01344 | HMPREF3232_00716 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.912 |
KXG88456.1 | murD | HMPREF3232_01344 | HMPREF3232_00713 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.993 |
KXG88456.1 | murG | HMPREF3232_01344 | HMPREF3232_00715 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.946 |
KXG90278.1 | KXG88456.1 | HMPREF3232_00711 | HMPREF3232_01344 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: ols:Olsu_1685 2.8e-108 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the MurCDEF family. MurE subfamily. | 0.999 |
KXG90278.1 | ddl | HMPREF3232_00711 | HMPREF3232_01397 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.997 |
KXG90278.1 | glmU | HMPREF3232_00711 | HMPREF3232_01231 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.667 |
KXG90278.1 | mraY | HMPREF3232_00711 | HMPREF3232_00712 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.999 |
KXG90278.1 | murA | HMPREF3232_00711 | HMPREF3232_00952 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.876 |
KXG90278.1 | murB | HMPREF3232_00711 | HMPREF3232_01222 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.927 |
KXG90278.1 | murC | HMPREF3232_00711 | HMPREF3232_00716 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.985 |
KXG90278.1 | murD | HMPREF3232_00711 | HMPREF3232_00713 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.994 |
KXG90278.1 | murG | HMPREF3232_00711 | HMPREF3232_00715 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.992 |
KXG91248.1 | murA | HMPREF3232_00146 | HMPREF3232_00952 | KEGG: sor:SOR_1377 9.3e-142 licA; choline kinase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.790 |
KXG91248.1 | murB | HMPREF3232_00146 | HMPREF3232_01222 | KEGG: sor:SOR_1377 9.3e-142 licA; choline kinase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.873 |